Thomas Worthington (11 April 1826 – 9 November 1909) was a 19th-century English architect, particularly associated with public buildings in and around Manchester. Worthington's preferred style was the Gothic Revival.
Worthington was born in Crescent Parade, Crescent, Salford, Lancashire, on 11 April 1826. He was the fourth of six sons of a Salford Unitarian cotton merchant, also called Thomas, and his second wife Susanna (1792–1869). He left school, aged 14, and was articled to Henry Bowman, architect (Bowman & Crowther). Before he was twenty he had won two medals: one for a church design (Royal Society of Arts) and one for an essay on "Brick" (Royal Institute of British Architects). After completing his articles in 1847, he assisted William Tite who was building Carlisle railway station. On the suspension of this work in 1848, he went on an eight-month study tour to France, Italy and Switzerland accompanied by a friend, Henry A. Darbishire. Their journey took them through Tuscany, Latium and Campania; Worthington's notes and sketches from the trip provided him with a first-hand knowledge of Italian Gothic and Renaissance architecture, which give him inspiration for his own later work.
After returning to Manchester in October 1848, Worthington spent a short time gaining experience of quantity surveying, before opening his own architectural practice in King Street the following year.
Worthington was strongly influenced by his Unitarian upbringing, becoming committed to social reform and joining numerous learned societies, including the Manchester Literary and Philosophical Society, the Portico Library and the Royal Manchester Institution.