Sir Thomas Chaloner (1521 – 14 October 1565) was an English statesman and poet.
Thomas Chaloner was born in 1521 to Margaret Myddleton and Roger Challoner (c. 1490-1550), a descendant of the Denbighshire Chaloners. His father was a London silk merchant who lived at St Mary-at-Hill Street, Billingsgate. A courtier, Roger was a Gentleman-Usher of the Privy Chamber to King Henry VIII, a Teller of the Receipt of the Exchequer, and a Freeman of the City of London through the Worshipful Company of Mercers. Roger died in 1550 and was buried in the main body of the Church of St Dunstan-in-the-East. Sir Thomas's two brothers, Francis and John Challoner settled in Ireland where John became a prominent politician and administrator.
No details are known of Thomas Chaloner's youth except that he was educated at both Oxford and Cambridge (likely St John's College).
In 1540 he went, as secretary to Sir Henry Knyvett, to the court of Charles V, whom he accompanied in his expedition against Algiers in 1541, and was wrecked on the Barbary coast. In 1547 he joined in the expedition to Scotland, and was knighted, after the battle of Pinkie near Musselburgh, by the protector Somerset, whose patronage he enjoyed. In 1549 he was a witness against Edmund Bonner, bishop of London; in 1551 against Stephen Gardiner, bishop of Winchester; in the spring of the latter year he was sent as a commissioner to Scotland to conclude the Treaty of Norham, and again in March 1552. In 1553 he went with Sir Nicholas Wotton and Sir William Pickering on an embassy to France, but was recalled by Queen Mary on her accession.