Thailand Route 2
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| ทางหลวงแผ่นดินหมายเลข 2 | |
| ถนนมิตรภาพ Thanon Mittraphap "Friendship Highway" |
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| Route information | |
Part of 
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| Length: | 509.113 km (316.348 mi) |
| Existed: | 1957 – present |
| Major junctions | |
| Southwest end: |
Saraburi,  Phahonyothin Rd.
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| Northeast end: |
Nong Khai, Thai–Lao Friendship Bridge  Laos
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| Location | |
| Provinces: |
Saraburi, Nakhon Ratchasima Khon Kaen Udon Thani, Nong Khai |
| Highway system | |
| Motorways | |
Mittraphap Road (Thai: ถนนมิตรภาพ, Thanon Mittraphap) or Thailand Route 2 (Thai: ทางหลวงแผ่นดินหมายเลข 2, Thang Luang Phaen Din Mai Lek 2) is one of the four major highways in Thailand, along with Phahonyothin Road (Route 1), Sukhumvit Road (Route 3), and Phetkasem Road (Route 4). It runs from Saraburi to Nong Khai. It was built with financial assistance from the United States of America.
It is the first highway in Thailand to meet international standards, and the first highway in Thailand to use both asphalt and concrete. It received the name "Thanon Mittraphap" on February 20, 1957. The name literally means "Friendship Road". It is the main road that connects Isan (northeastern Thailand) across the Dong Phaya Yen Range with Saraburi. It passes through the provinces of Nakhon Ratchasima, Khon Kaen, Udon Thani, and ends in Nong Khai, where it links with the Thai-Lao Friendship Bridge to Laos (subsidised by Australia government).
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