Texas State Highway 110
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| Route information | ||||
| Maintained by TxDOT | ||||
| Length: | 77.34 mi (124.47 km) | |||
| Existed: | by 1933 – present | |||
| Major junctions | ||||
| South end: |
 US 84 at Rusk
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 US 79 US 69 I-20
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| North end: |
 US 80 at Grand Saline
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State Highway 110 or SH 110 is a state highway in the U.S. state of Texas that runs from Grand Saline to Rusk.
SH 110 begins at an intersection with US 84 and Loop 62 in downtown Rusk and leaves the courthouse square north with US 84, crossing US 69 on its way to a split on the northeast side of Rusk where US 84 goes off east and SH 110 turns north, out of town. The road intersects with SH 204 in Ponta. The road intersects with U.S. Highway 79 in New Summerfield before crossing the county line into Smith County as it enters Troup. After a brief downtown multiplex with SH 135, SH 110 leaves Troup going northwest through Whitehouse on its way to Tyler. SH 110 swings around the downtown area to the south and west by way of multiplexes with SH 64, SH 155, and US 69. After splitting with US 69, SH 110 leaves Tyler toward the northwest. After several miles, SH 110 crosses I-20 south of Garden Valley. Just after Garden Valley, the road multiplexes with FM 16 and goes west into Van Zandt County. SH 110 splits with FM 16 in Van and turns back north. Approaching Grand Saline, SH 110 merges with FM 17 and travels the remaining several blocks multiplexed until it reaches US 80, the northern terminus of SH 110.
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