Tenascin-R

TNR

Identifiers

TNR, TN-R, tenascin R

External IDs

MGI: 99516 HomoloGene: 124416 GeneCards: TNR

Gene ontology
Molecular function	• protein binding
Cellular component	• extracellular region • proteinaceous extracellular matrix • cell surface • membrane raft • perineuronal net
Biological process	• negative regulation of neuron projection development • positive regulation of synaptic transmission, glutamatergic • extracellular matrix organization • axon guidance • synapse organization • positive regulation of transmission of nerve impulse • neuron cell-cell adhesion • negative regulation of cell-cell adhesion • telencephalon cell migration • negative regulation of axon extension • locomotory exploration behavior • long-term synaptic potentiation • neuromuscular process controlling balance • regulation of neurogenesis • negative regulation of axon extension involved in regeneration • negative regulation of synaptic transmission • modulation of synaptic transmission • associative learning • cell adhesion
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


7143


21960

Ensembl


ENSG00000116147


ENSMUSG00000015829

UniProt


Q92752


Q8BYI9

RefSeq (mRNA)


NM_003285 NM_001328635


NM_022312

RefSeq (protein)


NP_001315564 NP_003276 NP_003276.3


NP_071707.2 NP_071707

Location (UCSC)

Chr 1: 175.32 – 175.74 Mb

Chr 1: 159.52 – 159.93 Mb

PubMed search

NM_003285
NM_001328635

NM_022312

NP_001315564
NP_003276
NP_003276.3

NP_071707.2
NP_071707

Tenascin-R is a protein that in humans is encoded by the TNR gene.

Tenascin-R (TNR) is an extracellular matrix protein expressed primarily in the central nervous system. It is a member of the tenascin (TN) gene family, which includes at least 3 genes in mammals: TNC (or hexabrachion), TNX (TNXB), and TNR. The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues.[supplied by OMIM]

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