TRPV3

TRPV3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4N5Q
Identifiers
Aliases	TRPV3, FNEPPK2, OLMS, VRL3, transient receptor potential cation channel subfamily V member 3
External IDs	OMIM: 607066 MGI: 2181407 HomoloGene: 17040 GeneCards: TRPV3
Gene ontology Molecular function • ion channel activity • cation channel activity • calcium channel activity Cellular component • integral component of membrane • receptor complex • plasma membrane • membrane • integral component of plasma membrane Biological process • positive regulation of calcium ion import • response to heat • ion transport • calcium ion transmembrane transport • calcium ion transport • negative regulation of hair cycle • response to temperature stimulus • transport • transmembrane transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	162514	246788
Ensembl	ENSG00000167723	ENSMUSG00000043029
UniProt	Q8NET8	Q8K424
RefSeq (mRNA)	NM_001258205 NM_145068	NM_145099
RefSeq (protein)	NP_001245134 NP_659505	NP_659567.2 NP_659567
Location (UCSC)	Chr 17: 3.51 – 3.56 Mb	Chr 11: 73.27 – 73.3 Mb
PubMed search

4N5Q

162514

246788

ENSG00000167723

ENSMUSG00000043029

Q8NET8

Q8K424

NM_001258205
NM_145068

NM_145099

NP_001245134
NP_659505

NP_659567.2
NP_659567

Transient receptor potential cation channel, subfamily V, member 3, also known as TRPV3, is a human gene encoding the protein of the same name.

The TRPV3 protein belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. The gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels.

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