TPTE

TPTE
Identifiers
Aliases	TPTE, CT44, PTEN2, transmembrane phosphatase with tensin homology
External IDs	GeneCards: TPTE
Gene location (Human) Chr. Chromosome 21 (human) Band 21p11.2 Start 10,521,553 bp End 10,606,140 bp
Gene ontology Molecular function • protein tyrosine phosphatase activity • phosphoprotein phosphatase activity • hydrolase activity • protein tyrosine/serine/threonine phosphatase activity Cellular component • integral component of membrane • membrane Biological process • signal transduction • dephosphorylation • peptidyl-tyrosine dephosphorylation • protein dephosphorylation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7179	n/a
Ensembl	ENSG00000274391	n/a
UniProt	P56180	n/a
RefSeq (mRNA)	NM_199261 NM_001290224 NM_199259 NM_199260	n/a
RefSeq (protein)	NP_001277153 NP_954868 NP_954869 NP_954870	n/a
Location (UCSC)	Chr 21: 10.52 – 10.61 Mb	n/a
PubMed search		n/a

7179

n/a

ENSG00000274391

n/a

P56180

n/a

NM_199261
NM_001290224
NM_199259
NM_199260

n/a

NP_001277153
NP_954868
NP_954869
NP_954870

n/a

Putative tyrosine-protein phosphatase TPTE is an enzyme that in humans is encoded by the TPTE gene.

TPTE is a member of a large class of membrane-associated phosphatases with substrate specificity for the 3-position phosphate of inositol phospholipids. TPTE is a primate-specific duplicate of the TPTE2 (TPIP) inositol phospholipd phosphatase; TPTE itself is predicted to lack phosphatase activity. TPTE and TPTE2 are the mammalian homologues to the subfamily of voltage sensitive phosphatases.

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Wikipedia