Swiss Global Air Lines (until February 2015 Swiss European Air Lines) is a Swiss airline and a subsidiary of Swiss International Air Lines and therefore also of the Lufthansa Group. Like its parent, Swiss Global is part of the Star Alliance. It has its legal headquarters in Basel; the physical head office is on the grounds of Zurich Airport and the town of Kloten.

Swiss Global Air Lines operates scheduled flights in the name and corporate design of its parent Swiss International to European metropolitan and some leisure destinations from Zürich Airport as well as some long-haul routes on behalf of its parent.

Swiss Global Air Lines was founded in 2005 as Swiss European Air Lines, to operate European routes for its parent company.

On 11 March 2009, the Lufthansa Group board announced that it planned to gradually replace the current Avro RJ100 fleet flown by Swiss Global with aircraft of the Bombardier CSeries from 2014. The replacement of the twenty RJ100s was planned to take two years, while an additional ten aircraft would be delivered thereafter to allow for capacity expansion. The new aircraft would allow Swiss to continue serving restricted destinations such as London City Airport or Florence Perétola Airport. With the delays to the Bombardier CSeries' development this date was postponed to 2015. It was further postponed, with the first delivery, of a CS100, taking place in June 2016 with the first revenue flight on 15 July. The Lufthansa Group is a launch customer for this aircraft type, and had previously signed a letter of intent for up to 60 aircraft.

In December 2014, Swiss announced it would cease operations from EuroAirport Basel–Mulhouse–Freiburg altogether by 31 May 2015, including Swiss Global Air Lines' operations there; and subsequently concentrated on its operations in Zürich.

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