"Supernatural Superserious" is a song by American alternative rock band R.E.M.. It is the first single and third track from the band's fourteenth album Accelerate and premiered on now defunct New York City radio station WRXP on February 5, 2008, without the consent of Warner Bros. Records. The single was first released on February 11, 2008 as an MP3, and February 25, 2008 on CD. Like most of the songs on Accelerate, it made its debut during the band's "working rehearsals" at the Olympia Theatre in Dublin between June 30 and July 5, 2007, in an unfinished form with the name "Disguised"; the song appears on Live at The Olympia in this form. Its title was changed on the advice of Coldplay frontman Chris Martin.

The song itself proved an early success, entering the UK Singles Chart at number 54 on downloads, before its official physical release, although—unlike most of R.E.M.'s lead singles in the UK—it was not a hit there. It also became R.E.M.'s first song since 2001's "Imitation of Life" to enter more than two charts and to chart on the Billboard Modern Rock Tracks, with an entry position of number 36, eventually reaching 21. The other chart that the song charted was the Billboard Hot 100 where it reached number 85. It is also the band's final appearance on the Hot 100 chart.

The song was used by ESPN as part of their coverage of Major League Baseball's 2008 Opening Day. It was also featured in the film He's Just Not That Into You.

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