Staphylococcus aureus | |
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Scanning electron micrograph of S. aureus; false color added | |
Scientific classification | |
Domain: | Bacteria |
Kingdom: | Eubacteria |
Phylum: | Firmicutes |
Class: | Bacilli |
Order: | Bacillales |
Family: | Staphylococcaceae |
Genus: | Staphylococcus |
Species: | S. aureus |
Binomial name | |
Staphylococcus aureus Rosenbach 1884 |
Staphylococcus aureus | |
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Classification and external resources | |
Specialty | Infectious disease |
ICD-9-CM | 041.11 |
Staphylococcus aureus is a gram-positive coccal bacterium that is a member of the Firmicutes, and is frequently found in the nose, respiratory tract, and on the skin. It is often positive for catalase and nitrate reduction and is a facultative aerobe that can grow without the need for oxygen. Although S. aureus is not always pathogenic, it is a common cause of skin infections such as abscesses, respiratory infections such as sinusitis, and food poisoning. Pathogenic strains often promote infections by producing potent protein toxins, and expressing cell-surface proteins that bind and inactivate antibodies. The emergence of antibiotic-resistant strains of S. aureus such as methicillin-resistant S. aureus (MRSA) is a worldwide problem in clinical medicine.
Staphylococcus was first identified in 1880 in Aberdeen, Scotland, by the surgeon Sir Alexander Ogston in pus from a surgical abscess in a knee joint. This name was later amended to Staphylococcus aureus by Friedrich Julius Rosenbach, who was credited by the official system of nomenclature at the time. An estimated 20% of the human population are long-term carriers of S. aureus which can be found as part of the normal skin flora and in the nostrils.S. aureus is a normal inhabitant of the healthy lower reproductive tract of women.S. aureus can cause a range of illnesses, from minor skin infections, such as pimples,impetigo, boils, cellulitis, folliculitis, carbuncles, scalded skin syndrome, and abscesses, to life-threatening diseases such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome, bacteremia, and sepsis. It is still one of the five most common causes of hospital-acquired infections and is often the cause of postsurgical wound infections. Each year, around 500,000 patients in hospitals of the United States contract a staphylococcal infection, chiefly by S. aureus.