St. Francisville is an unincorporated community and census-designated place in Clark County, Missouri, in the United States. As of the 2010 census it had a population of 179.
St. Francisville was laid out in 1833, by a man of the name Francis Church.
Coordinates: 40°27′30″N 91°34′08″W / 40.4584°N 91.5690°W