Splice (film)
| Splice | |
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Final theatrical poster
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| Directed by | Vincenzo Natali |
| Produced by | Steve Hoban |
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| Starring | |
| Music by | Cyrille Aufort |
| Cinematography | Tetsuo Nagata |
| Edited by | Michele Conroy |
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Production
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| Distributed by | Warner Bros. Pictures |
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Release date
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Running time
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104 minutes |
| Country | |
| Language | English |
| Budget | $30 million |
| Box office | $26.9 million |
Splice is a 2009 Canadian-French science fiction horror film directed by Vincenzo Natali and starring Adrien Brody, Sarah Polley, and Delphine Chanéac. The story concerns experiments in genetic engineering being done by a young scientific couple, who attempt to introduce human DNA into their work of splicing animal genes.Guillermo del Toro, Don Murphy, and Joel Silver executive produced.
Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by splicing animal DNA to create hybrids for medical use at the company N.E.R.D. (short for Nucleic Exchange Research and Development). Their work previously yielded Fred, a dog-sized vermiform creature intended as a mate for their female specimen, Ginger. After successfully mating them, Clive and Elsa plan to create a human-animal hybrid that could revolutionize science. Their employers Joan Chorot of N.E.R.D. and William Barlow forbid them to do this. Instead, they are to find and extract proteins used for commercial drug production from Fred and Ginger. Clive and Elsa pursue their own agenda in secret. They develop a viable prepubescent female creature.
Although they had planned to terminate the hybrid before it reached full term, Elsa persuades Clive to let it live. The hybrid subsequently becomes aggressive and stings Elsa several times. The hybrid sheds body parts in an effort to escape when they try to destroy her, but they subdue her. They discover that she is aging at a vastly accelerated rate. Elsa discovers that the creature is undergoing mental development such as that of a young human child. Elsa names the creature "Dren" after the creature spells out NERD, having seen the letters on Elsa's shirt. Elsa subsequently refuses to let Clive refer to her as a "specimen".
After moving Dren to a new location for fear of discovery, they find she has a dangerously high fever. In an attempt to save her they place her in a large industrial sink full of cold water. Clive places a hand around Dren's neck and pushes her under the water, seemingly drowning her. However, it is found that Dren is amphibious, though it is unclear whether Clive knew this, having analysed scans of Dren, or whether he did intend to kill her.
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