South Carolina Highway 53
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| Route information | ||||
| Maintained by SCDOT | ||||
| Length: | 12.0 mi (19.3 km) | |||
| Major junctions | ||||
| South end: |
 US 378 southwest of Shiloh
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  I-95 / SC 58 in Shiloh SC 341 northeast of Shiloh |
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| North end: |
 SC 403 northeast of Shiloh |
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| Location | ||||
| Counties: | Sumter | |||
| Highway system | ||||
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South Carolina Highway 53 (SC 53) is a 12.0-mile-long (19.3 km) state highway in the U.S. state of South Carolina. The highway connects Shiloh with rural areas of Sumter County.
SC 53 begins at an intersection with US 378 (Myrtle Beach Highway) southwest of Shiloh, within Sumter County. It travels to the northeast, through rural areas of the county, and curves to a nearly due east direction. It intersects SC 58 (Pleasant Grove Road), and the two highways begin a concurrency. They have an interchange with Interstate 95 (I-95), where they enter Shiloh. Approximately 500 feet (150 m) later, SC 53 splits off to the south, onto Pudding Swamp Road. SC 53 continues through rural areas of the county to an intersection with SC 341 (Mt. Zion Road). About 2,000 feet (610 m) later is the highway's northern terminus, an intersection with SC 403 (Lynches River Road/Amwell Church Road). This is southwest of the Lynches River.
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