Sisters Keepers were initially a subset of the band Brothers Keepers, formed in the autumn of 2001 in Germany, joined a compilation album Lightkultur (WEA) by the Brothers Keepers. Appealing against racism, famous female and mainly Afro-German singers joined together with reggae, Soul music and Hip-Hop background.
Among others for the members of the original Sisters Keepers were Nadja Benaissa, Ayọ, Kaye, Nicole Hadfield (Groove Guerrilla ), and Tamika, along with Tesiree, Lisa, Mamadee, Pat and Meli (Skills en Masse, Ischen Impossible) with Onejiru (Pielina Schindler). "Liebe Und Verstand" was their largest hit on chart in Germany, Swiss and Austria between December 2001 to February 2002, as many African artists joined together to form a musical statement. With two songs, both released on the album Lightkultur by Brothers Keepers (WEA), they took a stand against racism and violence.
Actually, the members held positions among loose circle of network of female singers, or sisters.
Starting in 2004, the "Sisters eV" functioned with emphasis on activities for gender equality as well as protest against violence and racism, and environmental issues that Onejiru and Mamadee took the initiative. Among the list of female singers they worked with, Ngosi Madubuko and Angela Ordu are from Siberian music, who were two of the supporters close to the group.
In 2005, Sisters Keepers was renamed to "Sisters", and acted independent from Brothers Keepers there on. The Sisters started with Onejiru, Mamadee, Meli, Namusoke, Tamika and Nicole Hadfield (Groove Guerilla) and Lisa Cash coming in and out, and they represented North Rhine-Westphalia at the Bundesvision Song Contest 2008 to claim he fourteenth place with "Unite". In September 2008, they toured Germany, produced by Matthias Arfmann (Turtle Bay Country Club.) The same year, the first album Gender Riot was released.