Sir Anthony Cooke (1504 – 11 June 1576) was an eminent English humanist scholar. He was tutor to Edward VI.
Anthony Cooke was the only son of John Cooke (died 10 October 1515), esquire, of Gidea Hall, Essex, and Alice Saunders (died 1510), daughter and coheiress of William Saunders of Banbury, Oxfordshire by Jane Spencer, daughter of John Spencer, esquire, of Hodnell, Warwickshire. His paternal grandparents were Sir Philip Cooke (died 7 December 1503) and Elizabeth Belknap (died c. 6 March 1504). His paternal great-grandparents were Sir Thomas Cooke, a wealthy member of the Worshipful Company of Drapers and Lord Mayor of London in 1462–3, and Elizabeth Malpas, daughter of Philip Malpas, Master of the Worshipful Company of Drapers and Sheriff of London.
Cooke served as High Sheriff of Essex in 1545.
He was never officially described as tutor to Edward VI. It is now thought he may have been more a companion and guide than a formal teacher. However, in 1555 Caelius Secundus Curio, in his dedication letter to Cooke of Sir John Cheke's De Pronuntiatione Graecae, wrote that "the boyhood of King Edward was handed over and entrusted to the two of you for instruction in letters, behaviour and religion... from you that divine boy drank in that learning, than which not Cyrus, nor Achilles, nor Alexander, nor any king ever received more wholesome and sacred."Peter Martyr, in dedicating to Cooke his Commentaries on St Paul's Epistle to the Romans (published 1558), wrote: "I for my part doubtles have, ever since that the time that I dwelt in England, borne a singular love and no smal or vulgar affection towards you, both for your singular piety and learning, and also for the worthy office which you faythfully and with great renoune executed in the Christian publike wealth, in instructing Edward, that most holy King..."