Severe fever with thrombocytopenia syndrome

Severe fever with thrombocytopenia syndrome
Classification and external resources
ICD-10	A99
ICD-9-CM	065.9
MeSH	D002044
[]

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease recently discovered in northeast and central China. SFTS has fatality rates ranging from 12% to as high as 30% in some areas. The major clinical symptoms of SFTS are fever, vomiting, diarrhea, multiple organ failure, thrombocytopenia (low platelet count), leucopenia (low white blood cell count), and elevated liver enzyme levels.

SFTS virus (SFTSV) is a Phlebovirus in the family of Bunyaviridae. The transmission route of SFTSV is unknown, but person-to-person transmission either plays no role or at least is not an important routine of transmission of SFTSV.

The life cycle of the SFTSV most likely involves arthropod vectors and animal hosts. Humans appear to be accidental hosts and play no role in the life cycle of the SFTSV. SFTSV has been detected in Haemaphysalis longicornis ticks.

SFTS occurs in China's rural areas from March to November with the majority of cases from April to July. In 2013, Japan and Korea also reported several cases with deaths.

July 2013 - South Korea reports death toll of 8 since Aug 2012

The virus originated 50–150 years ago and has undergone a recent population expansion.

In 2009 Xue-jie Yu and colleagues isolated the SFTS virus (SFTSV) from SFTS patients’ blood.

...
Wikipedia