"Scream & Shout" is a song by American recording artists will.i.am and Britney Spears, taken from the former's fourth studio album #willpower. It was released on November 20, 2012 by Interscope Records as the second single from the album, and sent to mainstream radio in the United States on November 27. The song was written by will.i.am, Jef Martens and Jean Baptiste and was produced by Martens under the alias Lazy Jay, with additional production by will.i.am. "Scream & Shout" is an upbeat dance-pop song; its lyrics are about having a good time on a night out. It interpolates a sample of the lyric "Britney, bitch", which was used on Spears' 2007 single "Gimme More".

"Scream & Shout" received mixed reviews from music critics. Some critics described the song as a dark club track, but others criticized the use of Auto-Tune on the vocals. The song was a commercial success worldwide, topping the charts in over 24 countries and reached the top ten in Australia, Sweden, and South Korea. In the United States, the song peaked at number three on the Billboard Hot 100 and became the first number one song of the newly established Dance/Electronic Songs chart. In the United Kingdom, "Scream & Shout" became will.i.am's second consecutive number one single, Spears' sixth number one and her first chart-topper since "Everytime."

An accompanying music video directed by Ben Mor was shot in October 2012, and premiered in the U.S. during a live episode of The X Factor on November 28. The theme of the music video is multiplicity, and critics complimented its futuristic setting. "Scream & Shout" also served as the theme song for a television commercial for Beats by Dr. Dre Color headphones. A remixed version of the song, featuring rappers Hit-Boy, Waka Flocka Flame, Lil Wayne and Sean Combs, was uploaded to will.i.am's official YouTube account on January 25, 2013, after it was leaked on the internet earlier the same day. A music video for this version was filmed in January 2013 and released on February 14.

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