Samuel Simpson Sharpe DSO (March 13, 1873 – May 25, 1918) was a lawyer and political figure in Ontario, Canada. He represented Ontario North in the Canadian House of Commons from 1909 to 1917 as a Conservative and from 1917 to 1918 as a Unionist Party member.
He was born in Zephyr, Ontario, the son of George Sharpe, a native of England, and Mary Ann Simpson, a native of Ireland. Sharpe was educated in Uxbridge, at the University of Toronto and Osgoode Hall. In 1903, he married Mabel E. Crosby, a granddaughter of Joseph Gould. Sharpe practised law in Uxbridge and was town solicitor for 10 years.
Sharpe commanded a battalion which served overseas in France during World War I. He was awarded the Distinguished Service Order in the 1918 New Year Honours for his service during the war.
Sharpe died in office in Montreal at the age of 45.
His brother William Henry Sharpe served in the House of Commons and Senate.