SUMO-1

SUMO1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4WJQ, 1A5R, 1TGZ, 1WYW, 1Y8R, 1Z5S, 2ASQ, 2BF8, 2G4D, 2IO2, 2IY0, 2IY1, 2KQS, 2LAS, 2MW5, 2PE6, 2UYZ, 2VRR, 3KYC, 3KYD, 3RZW, 3UIP, 4WJN, 4WJO, 4WJP, 5AEK, 2N1V, 2N1A
Identifiers
Aliases	SUMO1, DAP1, GMP1, OFC10, PIC1, SENP2, SMT3, SMT3C, SMT3H3, UBL1, small ubiquitin-like modifier 1
External IDs	OMIM: 601912 MGI: 1197010 HomoloGene: 2514 GeneCards: SUMO1
Gene location (Human) Chr. Chromosome 2 (human) Band 2q33.1 Start 202,206,180 bp End 202,238,608 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1|1 C2 Start 59,586,558 bp End 59,670,834 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • transcription factor binding • potassium channel regulator activity • protein binding • protein tag • ubiquitin protein ligase binding • RNA binding • transcription corepressor binding • protein C-terminus binding • SUMO transferase activity • enzyme binding • protein binding, bridging • glucocorticoid receptor binding • small protein activating enzyme binding Cellular component • cytoplasm • PML body • nuclear speck • nuclear body • nuclear membrane • membrane • voltage-gated potassium channel complex • plasma membrane • synapse • nuclear pore • nucleoplasm • heterochromatin • XY body • dendrite • nucleolus • fibrillar center • nucleus • nuclear stress granule • SUMO activating enzyme complex Biological process • palate development • regulation of transcription, DNA-templated • regulation of protein stability • positive regulation of protein complex assembly • protein localization to nuclear pore • protein stabilization • negative regulation of action potential • negative regulation of sequence-specific DNA binding transcription factor activity • regulation of protein localization • regulation of cardiac muscle cell contraction • global genome nucleotide-excision repair • PML body organization • regulation of interferon-gamma-mediated signaling pathway • viral process • negative regulation of transcription, DNA-templated • double-strand break repair via nonhomologous end joining • regulation of calcium ion transmembrane transport • positive regulation of proteasomal ubiquitin-dependent protein catabolic process • negative regulation of delayed rectifier potassium channel activity • positive regulation of calcium-transporting ATPase activity • DNA repair • negative regulation of transcription from RNA polymerase II promoter • cellular response to heat • cellular response to cadmium ion • protein sumoylation • negative regulation of DNA binding Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7341	22218
Ensembl	ENSG00000116030	ENSMUSG00000026021
UniProt	P63165	P63166
RefSeq (mRNA)	NM_003352 NM_001005781 NM_001005782	NM_009460
RefSeq (protein)	NP_001005781 NP_001005782 NP_003343	NP_033486
Location (UCSC)	Chr 2: 202.21 – 202.24 Mb	Chr 2: 59.59 – 59.67 Mb
PubMed search

4WJQ, 1A5R, 1TGZ, 1WYW, 1Y8R, 1Z5S, 2ASQ, 2BF8, 2G4D, 2IO2, 2IY0, 2IY1, 2KQS, 2LAS, 2MW5, 2PE6, 2UYZ, 2VRR, 3KYC, 3KYD, 3RZW, 3UIP, 4WJN, 4WJO, 4WJP, 5AEK, 2N1V, 2N1A

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