SULT2B1a

SULT2B1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1Q1Q, 1Q1Z, 1Q20, 1Q22
Identifiers
Aliases	SULT2B1, HSST2, sulfotransferase family 2B member 1, ARCI14
External IDs	MGI: 1926342 HomoloGene: 49487 GeneCards: SULT2B1
Gene ontology Molecular function • transferase activity • sulfotransferase activity • protein binding • alcohol sulfotransferase activity • steroid sulfotransferase activity • nucleic acid binding • cholesterol binding • steroid hormone binding Cellular component • extracellular exosome • endoplasmic reticulum • intracellular membrane-bounded organelle • nucleus • cytoplasm • cytosol Biological process • steroid metabolic process • sulfate assimilation • lipid metabolic process • 3'-phosphoadenosine 5'-phosphosulfate metabolic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6820	54200
Ensembl	ENSG00000088002	ENSMUSG00000003271
UniProt	O00204	O35400
RefSeq (mRNA)	NM_004605 NM_177973	NM_017465
RefSeq (protein)	NP_004596 NP_814444	NP_059493
Location (UCSC)	Chr 19: 48.55 – 48.6 Mb	Chr 7: 45.73 – 45.78 Mb
PubMed search

1Q1Q, 1Q1Z, 1Q20, 1Q22

6820

54200

ENSG00000088002

ENSMUSG00000003271

O00204

O35400

NM_004605
NM_177973

NM_017465

NP_004596
NP_814444

NP_059493

Sulfotransferase family cytosolic 2B member 1 is an enzyme that in humans is encoded by the SULT2B1 gene.

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic chemical compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described.

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