STXBP1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3PUJ

Identifiers

STXBP1, MUNC18-1, NSEC1, P67, RBSEC1, UNC18, syntaxin binding protein 1

External IDs

Gene ontology
Molecular function	• protein domain specific binding • protein N-terminus binding • syntaxin-1 binding • protein binding • identical protein binding • syntaxin binding • protein kinase binding • SNARE binding • RNA binding
Cellular component	• platelet alpha granule • membrane • myelin sheath • plasma membrane • nucleoplasm • protein complex • terminal bouton • mitochondrion • extracellular exosome • cytoplasm • cytosol • presynaptic active zone membrane • cell
Biological process	• negative regulation of neuron apoptotic process • exocytosis • axon target recognition • protein stabilization • platelet degranulation • positive regulation of calcium ion-dependent exocytosis • glutamate secretion • regulation of synaptic vesicle fusion to presynaptic membrane • neuromuscular synaptic transmission • negative regulation of synaptic transmission, GABAergic • long term synaptic depression • transport • protein transport • positive regulation of exocytosis • protein localization to plasma membrane • platelet aggregation • regulation of SNARE complex assembly • synaptic vesicle maturation • vesicle-mediated transport • neurotransmitter secretion • regulation of synaptic vesicle priming • vesicle docking involved in exocytosis • negative regulation of protein complex assembly • presynaptic dense core vesicle exocytosis
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


6812


20910


ENSG00000136854


ENSMUSG00000026797


P61764


O08599

RefSeq (mRNA)


NM_003165 NM_001032221


NM_001113569 NM_009295

RefSeq (protein)


NP_001027392 NP_003156


NP_001107041.1 NP_033321.2 NP_001107041 NP_033321

Location (UCSC)

PubMed search

Syntaxin-binding protein 1 is a protein that in humans is encoded by the STXBP1 gene.

In melanocytic cells STXBP1 gene expression may be regulated by MITF.