STARD13

STARD13
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2H80, 2JW2, 2PSO
Identifiers
Aliases	STARD13, ARHGAP37, DLC2, GT650, LINC00464, StAR related lipid transfer domain containing 13
External IDs	MGI: 2385331 HomoloGene: 64844 GeneCards: STARD13
Gene ontology Molecular function • protein binding • lipid binding • GTPase activator activity Cellular component • cytoplasm • cytosol • lipid droplet • mitochondrial membrane • mitochondrion • membrane Biological process • negative regulation of cell migration involved in sprouting angiogenesis • positive regulation of GTPase activity • endothelial tube lumen extension • regulation of small GTPase mediated signal transduction • endothelial cell migration • signal transduction Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	90627	243362
Ensembl	ENSG00000133121	ENSMUSG00000016128
UniProt	Q9Y3M8	Q923Q2
RefSeq (mRNA)	NM_001243466 NM_001243474 NM_001243476 NM_052851 NM_178006 NM_178007 NM_178008	NM_001163493 NM_146258
RefSeq (protein)	NP_001230395 NP_001230403 NP_001230405 NP_443083 NP_821074 NP_821075	NP_001156965 NP_666370
Location (UCSC)	Chr 13: 33.1 – 33.35 Mb	Chr 5: 151.04 – 151.23 Mb
PubMed search

2H80, 2JW2, 2PSO

90627

243362

ENSG00000133121

ENSMUSG00000016128

Q9Y3M8

Q923Q2

NM_178007
NM_178008

NM_001163493
NM_146258

NP_821075

NP_001156965
NP_666370

StAR-related lipid transfer domain protein 13 (STARD13) also known as deleted in liver cancer 2 protein (DLC-2) is a protein that in humans is encoded by the STARD13 gene and a member of the DLC family of proteins.

STARD13 serves as a Rho GTPase-activating protein (GAP), a type of protein that regulates members of the Rho family of GTPases. It selectively activates RhoA and CDC42 and suppresses cell growth by inhibiting actin stress fiber assembly.

...
Wikipedia