RhoA

RHOA
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5BWM, 1A2B, 1CC0, 1CXZ, 1DPF, 1FTN, 1KMQ, 1LB1, 1OW3, 1S1C, 1TX4, 1X86, 1XCG, 2RGN, 3KZ1, 3LW8, 3LWN, 3LXR, 3MSX, 3T06, 4D0N, 4XH9, 4XSG, 4XSH, 4XOI, 5A0F, 5FR2, 5FR1, 5JCP, 5C2K, 5C4M, 5HPY
Identifiers
Aliases	RHOA, ARH12, ARHA, RHO12, RHOH12, ras homolog family member A
External IDs	OMIM: 165390 MGI: 1096342 HomoloGene: 68986 GeneCards: RHOA
Gene ontology Molecular function • nucleotide binding • myosin binding • GTP binding • protein binding • GTPase activity Cellular component • cytoplasm • vesicle • cytosol • endosome • cell projection • endoplasmic reticulum membrane • membrane • focal adhesion • extrinsic component of cytoplasmic side of plasma membrane • plasma membrane • cell junction • cell cortex • midbody • cleavage furrow • cytoskeleton • apical junction complex • extracellular exosome • cell periphery • lamellipodium • secretory granule membrane • ficolin-1-rich granule membrane • intracellular Biological process • actin cytoskeleton reorganization • ossification involved in bone maturation • apolipoprotein A-I-mediated signaling pathway • regulation of cell migration • negative chemotaxis • regulation of actin cytoskeleton organization • cleavage furrow formation • substantia nigra development • ephrin receptor signaling pathway • endothelial tube lumen extension • Roundabout signaling pathway • positive regulation of axonogenesis • stress fiber assembly • positive regulation of lipase activity • regulation of osteoblast proliferation • cell division • positive regulation of cytokinesis • platelet activation • negative regulation of cell migration involved in sprouting angiogenesis • positive regulation of protein serine/threonine kinase activity • mitotic cleavage furrow formation • mitotic spindle assembly • negative regulation of axonogenesis • vascular endothelial growth factor receptor signaling pathway • skeletal muscle satellite cell migration • trabecula morphogenesis • positive regulation of neuron differentiation • Rho protein signal transduction • positive regulation of I-kappaB kinase/NF-kappaB signaling • cell cycle • positive regulation of NF-kappaB import into nucleus • viral process • regulation of small GTPase mediated signal transduction • transforming growth factor beta receptor signaling pathway • cell migration • apical junction assembly • wound healing, spreading of cells • endothelial cell migration • positive regulation of stress fiber assembly • actin cytoskeleton organization • phosphatidylinositol-mediated signaling • small GTPase mediated signal transduction • regulation of cell motility • Wnt signaling pathway, planar cell polarity pathway • protein deubiquitination • neutrophil degranulation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	387	11848
Ensembl	ENSG00000067560	ENSMUSG00000007815
UniProt	P61586	Q9QUI0
RefSeq (mRNA)	NM_001313941 NM_001313943 NM_001313944 NM_001313945 NM_001313946 NM_001313947 NM_001664	NM_016802 NM_001313961 NM_001313962
RefSeq (protein)	NP_001300870 NP_001300872 NP_001300873 NP_001300874 NP_001300875 NP_001300876 NP_001655 NP_001300870.1 NP_001655.1	NP_001300890.1 NP_001300891.1 NP_058082.2 NP_001300890 NP_001300891 NP_058082
Location (UCSC)	Chr 3: 49.36 – 49.41 Mb	Chr 9: 108.31 – 108.34 Mb
PubMed search

5BWM, 1A2B, 1CC0, 1CXZ, 1DPF, 1FTN, 1KMQ, 1LB1, 1OW3, 1S1C, 1TX4, 1X86, 1XCG, 2RGN, 3KZ1, 3LW8, 3LWN, 3LXR, 3MSX, 3T06, 4D0N, 4XH9, 4XSG, 4XSH, 4XOI, 5A0F, 5FR2, 5FR1, 5JCP, 5C2K, 5C4M, 5HPY

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