SRC-1

NCOA1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1FM6, 1FM9, 1K74, 1K7L, 1KV6, 1K4W, 1N4H, 1NQ7, 1NRL, 1P8D, 1PZL, 1RDT, 1TFC, 1U3R, 1U3S, 1X76, 1XIU, 1XV9, 1XVP, 1YY4, 1ZAF, 2A3I, 2C52, 2FVJ, 2GTK, 2HBH, 2HC4, 2HCD, 2HFP, 2NPA, 2NV7, 2P54, 2PRG, 3BEJ, 3BQD, 3CTB, 3CWD, 3DCT, 3DCU, 3DR1, 3ET1, 3ET3, 3FEI, 3FEJ, 3FUR, 3FXV, 3G8I, 3G9E, 3GYT, 3GYU, 3H0A, 3HC5, 3HC6, 3HVL, 3IPQ, 3IPS, 3IPU, 3KMR, 3LMP, 3OKH, 3OKI, 3OLF, 3OLL, 3OLS, 3OMK, 3OMM, 3OMO, 3OMP, 3OMQ, 3OOF, 3OOK, 3P88, 3P89, 3QT0, 3RUT, 3RUU, 3RVF, 3S9S, 3T03, 3UU7, 3UUA, 3UUD, 3V9Y, 3VN2, 4DK7, 4DK8, 4DM6, 4DM8, 4DQM, 4F9M, 4FGY, 4G1D, 4G1Y, 4G1Z, 4G20, 4G21, 4G2H, 4HEE, 4J5X, 4JYG, 4JYH, 4JYI, 4MG5, 4MG6, 4MG7, 4MG8, 4MG9, 4MGA, 4MGB, 4MGC, 4MGD, 4TUZ, 4TV1, 5AVI, 5AVL, 4Y29, 4RUJ, 4RUP, 5A86, 5E7V, 4UDB, 4UDA, 5AZT, 5HJS
Identifiers
Aliases	NCOA1, F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74, nuclear receptor coactivator 1
External IDs	MGI: 1276523 HomoloGene: 7859 GeneCards: NCOA1
Gene location (Human) Chr. Chromosome 2 (human) Band 2p23.3 Start 24,491,914 bp End 24,770,702 bp
Gene location (Mouse) Chr. Chromosome 12 (mouse) Band n/a Start 4,247,362 bp End 4,477,182 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • transferase activity • DNA binding • RNA polymerase II transcription coactivator activity • protein dimerization activity • progesterone receptor binding • protein N-terminus binding • protein complex binding • transcription coactivator activity • transcription factor binding • chromatin binding • nuclear hormone receptor binding • histone acetyltransferase activity • retinoid X receptor binding • protein binding • androgen receptor binding • ligand-dependent nuclear receptor binding • retinoic acid receptor binding • enzyme binding • transferase activity, transferring acyl groups • RNA polymerase II regulatory region DNA binding • estrogen receptor binding • ligand-dependent nuclear receptor transcription coactivator activity • aryl hydrocarbon receptor binding Cellular component • cytoplasm • nuclear chromatin • neuron projection • nucleus • nucleoplasm • cytosol • plasma • protein complex Biological process • androgen receptor signaling pathway • regulation of RNA biosynthetic process • male mating behavior • response to estradiol • male gonad development • regulation of transcription, DNA-templated • response to retinoic acid • cellular response to Thyroglobulin triiodothyronine • estrous cycle • regulation of cellular response to drug • response to progesterone • transcription, DNA-templated • cerebellum development • positive regulation of transcription, DNA-templated • labyrinthine layer morphogenesis • cellular response to hormone stimulus • positive regulation of neuron differentiation • bile acid and bile salt transport • hypothalamus development • cerebral cortex development • positive regulation of apoptotic process • histone H4 acetylation • response to hormone • lactation • hippocampus development • positive regulation of female receptivity • regulation of thyroid hormone mediated signaling pathway • positive regulation of transcription from RNA polymerase II promoter • intracellular receptor signaling pathway • positive regulation of transcription from RNA polymerase II promoter by galactose • regulation of lipid metabolic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8648	17977
Ensembl	ENSG00000084676	ENSMUSG00000020647
UniProt	Q15788	P70365
RefSeq (mRNA)	NM_003743 NM_147223 NM_147233	NM_010881
RefSeq (protein)	NP_003734 NP_671756 NP_671766	NP_035011
Location (UCSC)	Chr 2: 24.49 – 24.77 Mb	Chr 2: 4.25 – 4.48 Mb
PubMed search

1FM6, 1FM9, 1K74, 1K7L, 1KV6, 1K4W, 1N4H, 1NQ7, 1NRL, 1P8D, 1PZL, 1RDT, 1TFC, 1U3R, 1U3S, 1X76, 1XIU, 1XV9, 1XVP, 1YY4, 1ZAF, 2A3I, 2C52, 2FVJ, 2GTK, 2HBH, 2HC4, 2HCD, 2HFP, 2NPA, 2NV7, 2P54, 2PRG, 3BEJ, 3BQD, 3CTB, 3CWD, 3DCT, 3DCU, 3DR1, 3ET1, 3ET3, 3FEI, 3FEJ, 3FUR, 3FXV, 3G8I, 3G9E, 3GYT, 3GYU, 3H0A, 3HC5, 3HC6, 3HVL, 3IPQ, 3IPS, 3IPU, 3KMR, 3LMP, 3OKH, 3OKI, 3OLF, 3OLL, 3OLS, 3OMK, 3OMM, 3OMO, 3OMP, 3OMQ, 3OOF, 3OOK, 3P88, 3P89, 3QT0, 3RUT, 3RUU, 3RVF, 3S9S, 3T03, 3UU7, 3UUA, 3UUD, 3V9Y, 3VN2, 4DK7, 4DK8, 4DM6, 4DM8, 4DQM, 4F9M, 4FGY, 4G1D, 4G1Y, 4G1Z, 4G20, 4G21, 4G2H, 4HEE, 4J5X, 4JYG, 4JYH, 4JYI, 4MG5, 4MG6, 4MG7, 4MG8, 4MG9, 4MGA, 4MGB, 4MGC, 4MGD, 4TUZ, 4TV1, 5AVI, 5AVL, 4Y29, 4RUJ, 4RUP, 5A86, 5E7V, 4UDB, 4UDA, 5AZT, 5HJS

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