SNX1

SNX1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2I4K, 4FZS
Identifiers
Aliases	SNX1, HsT17379, VPS5, sorting nexin 1
External IDs	OMIM: 601272 MGI: 1928395 HomoloGene: 99716 GeneCards: SNX1
Gene ontology Molecular function • protein homodimerization activity • insulin receptor binding • leptin receptor binding • epidermal growth factor receptor binding • protein binding • phosphatidylinositol binding • identical protein binding • protein heterodimerization activity • transferrin receptor binding • lipid binding • cadherin binding Cellular component • cytoplasm • cytosol • Golgi apparatus • cell projection • early endosome membrane • membrane • retromer, tubulation complex • intracellular membrane-bounded organelle • protein complex • retromer complex • early endosome • endosome membrane • lamellipodium • extrinsic component of membrane • vesicle • lysosome • endosome Biological process • positive regulation of protein catabolic process • vesicle organization • early endosome to Golgi transport • receptor internalization • endosomal transport • retrograde transport, endosome to Golgi • transport • protein transport • intracellular protein transport • lamellipodium morphogenesis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6642	56440
Ensembl	ENSG00000028528	ENSMUSG00000032382
UniProt	Q13596	Q9WV80
RefSeq (mRNA)	NM_001242933 NM_003099 NM_148955 NM_152826	NM_019727
RefSeq (protein)	NP_001229862 NP_003090 NP_683758	NP_062701
Location (UCSC)	Chr 15: 64.09 – 64.15 Mb	Chr 9: 66.09 – 66.13 Mb
PubMed search

2I4K, 4FZS

6642

56440

ENSG00000028528

ENSMUSG00000032382

Q13596

Q9WV80

NM_001242933
NM_003099
NM_148955
NM_152826

NM_019727

NP_001229862
NP_003090
NP_683758

NP_062701

Sorting nexin-1 is a protein that in humans is encoded by the SNX1 gene. The protein encoded by this gene is a sorting nexin. SNX1 is a component of the retromer complex.

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Wikipedia