SIGLEC8

SIGLEC8
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2N7B, 2N7A
Identifiers
Aliases	SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L, sialic acid binding Ig like lectin 8
External IDs	MGI: 2681107 HomoloGene: 50482 GeneCards: SIGLEC8
Gene ontology Molecular function • protein binding • transmembrane signaling receptor activity • carbohydrate binding Cellular component • integral component of membrane • membrane Biological process • cell adhesion • signal transduction Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	27181	233186
Ensembl	ENSG00000105366	ENSMUSG00000039013
UniProt	Q9NYZ4	Q920G3
RefSeq (mRNA)	NM_014442	NM_001271019 NM_145581
RefSeq (protein)	NP_055257	NP_001257948.1 NP_663556.1 NP_001257948 NP_663556
Location (UCSC)	Chr 19: 51.45 – 51.46 Mb	Chr 7: 43.35 – 43.36 Mb
PubMed search

2N7B, 2N7A

27181

233186

ENSG00000105366

ENSMUSG00000039013

Q9NYZ4

Q920G3

NM_014442

NM_001271019
NM_145581

NP_055257

NP_001257948.1
NP_663556.1
NP_001257948
NP_663556

Sialic acid-binding Ig-like lectin 8 is a protein that in humans is encoded by the SIGLEC8 gene. This gene is located on chromosome 19q13.4, about 330 kb downstream of the SIGLEC9 gene. Within the siglec family of transmembrane proteins, Siglec-8 belongs to the CD33-related siglec subfamily, a subfamily that has undergone rapid evolution.

...
Wikipedia