SFPQ

LOC654780

Available structures

Human UniProt search: PDBe RCSB

List of PDB id codes
4WII, 4WIJ, 4WIK

Identifiers

LOC654780, POMP100, PPP1R140, PSF, SFPQ, splicing factor proline/glutamine-rich

External IDs

Gene ontology
Molecular function	• RNA polymerase II distal enhancer sequence-specific DNA binding • core promoter binding • histone deacetylase binding • chromatin binding • transcription regulatory region sequence-specific DNA binding • protein binding • nucleic acid binding • transcription regulatory region DNA binding • DNA binding • protein homodimerization activity • RNA binding
Cellular component	• cytoplasm • paraspeckles • nuclear matrix • RNA polymerase II transcription factor complex • chromatin • nucleus • nucleoplasm • extracellular matrix • nuclear speck
Biological process	• histone H3 deacetylation • DNA recombination • regulation of transcription, DNA-templated • rhythmic process • negative regulation of circadian rhythm • mRNA processing • negative regulation of transcription from RNA polymerase II promoter • chromosome organization • transcription, DNA-templated • cellular response to DNA damage stimulus • regulation of cell cycle • regulation of circadian rhythm • double-strand break repair via homologous recombination • RNA splicing • positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway • positive regulation of sister chromatid cohesion • negative regulation of transcription, DNA-templated • alternative mRNA splicing, via spliceosome • DNA repair • positive regulation of transcription from RNA polymerase II promoter
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


654780


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P23246


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RefSeq (mRNA)


NM_001039504


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RefSeq (protein)


NP_005057


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Location (UCSC)

n/a

PubMed search

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Splicing factor, proline- and glutamine-rich is a protein that in humans is encoded by the SFPQ gene.

SFPQ has been shown to interact with PTBP1,NONO,CDC5L and Ubiquitin C.