SB-204741

SB-204741

Identifiers
IUPAC name N-(1-Methyl-1H-indol-5-yl)-N'-(3-methylisothiazol-5-yl)urea
Synonyms	SB-204,741
CAS Number	152239-46-8 Y
PubChem CID	3277600
IUPHAR/BPS	221
ChemSpider	2526822
ECHA InfoCard	100.150.276
Chemical and physical data
Formula	C14H14N4OS
Molar mass	286.352 g/mol
3D model (Jmol)	Interactive image
SMILES c2c(C)nsc2NC(=O)Nc3ccc1n(C)ccc1c3
InChI InChI=1S/C14H14N4OS/c1-9-7-13(20-17-9)16-14(19)15-11-3-4-12-10(8-11)5-6-18(12)2/h3-8H,1-2H3,(H2,15,16,19) Key:USFUFHFQWXDVMH-UHFFFAOYSA-N

SB-204741 is a drug which acts as a potent and selective antagonist at the serotonin 5-HT_2B receptor, with around 135x selectivity over the closely related 5-HT_2C receptor, and even higher over the 5-HT_2A receptor and other targets. It is used in scientific research for investigating the functions of the 5-HT_2B receptor.