National Route 40 or RN40, often called Ruta 40 even in English texts, is a route in western Argentina, stretching from Punta Loyola near Rio Gallegos in Santa Cruz Province in the south to La Quiaca in Jujuy Province in the north, running parallel to the Andes mountains. The southern part of the route, a largely unpaved road through sparsely populated territory, has become a well-known adventure tourism journey, although it is now planned to pave the whole road.
Route 40 is the longest route in Argentina and one of the longest in the world (along with the U.S. Route 66, Canada's Trans-Canada Highway and the Stuart Highway in Australia—without counting the unofficial Panamerican Highway), more than 5,000 km (3,107 mi) long. At its traditional southern end near the city of Río Gallegos it starts at sea level, crosses 20 national parks, 18 major rivers, 27 passes on the Andes, and goes up to 5,000 m (16,404 ft) above sea level in Abra del Acay in Salta.
The road crosses the provinces of Santa Cruz, Chubut, Río Negro, Neuquen, Mendoza, San Juan, La Rioja, Catamarca, Tucumán, Salta and Jujuy.