Rudolph E. Tanzi

Rudolph Tanzi (also Rudy Tanzi) is the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard University, and Director of the Genetics and Aging Research Unit at Massachusetts General Hospital (MGH). Tanzi has been investigating the genetics of neurological disease since a student in the 1980s when he participated in the first study that used genetic markers to find a disease gene (Huntington's disease). Tanzi co-discovered all three familial early-onset Alzheimer's disease (FAD) genes and several other neurological disease genes including that responsible for Wilson’s disease. As the leader of the Cure Alzheimer's Fund Alzheimer’s Genome Project, Tanzi has carried out multiple genome wide association studies of thousands of Alzheimer’s families leading to the identification of novel AD candidate genes, including CD33 and the first two rare mutations causing late-onset AD in the ADAM10 gene. His research on the role of zinc and copper in AD has led to clinical trials at Prana Biotechnology. He is also working on gamma secretase modulators (together with Steve Wagner, UCSD) for the prevention and treatment of Alzheimer's.

Dr. Tanzi has published roughly 500 scientific papers including the top three most cited papers in the field of Alzheimer's disease research. Dr. Tanzi also co-authored the books "Decoding Darkness: The Search the Genetic Causes of Alzheimer's Disease, the New York Times Best Seller book “Super Brain: Unleashing the Explosive Power of Your Mind to Maximize Health, Happiness, and Spiritual Well-Being" Paperback – October 22, 2013” and the International best seller: "Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being" with Deepak Chopra. Tanzi has made numerous television appearances on shows such as CBS This Morning and Dr. Oz. He also hosts the shows "Super Brain with Dr. Rudy Tanzi" and "Super Genes with Dr. Rudy Tanzi" on PBS television.

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