The Diocese of Sansepolcro was a Roman Catholic diocese in Italy.
It was erected in 1515 and in 1986 was united with the Diocese of Arezzo and the Diocese of Cortona to form the Diocese of Arezzo-Cortona-Sansepolcro.
This article incorporates text from a publication now in the public domain: Herbermann, Charles, ed. (1913). "". Catholic Encyclopedia. New York: Robert Appleton.