Rnd2

RND2
Identifiers
Aliases	RND2, ARHN, RHO7, RhoN, Rnd2, Rho family GTPase 2
External IDs	MGI: 1338755 HomoloGene: 21123 GeneCards: RND2
Gene ontology Molecular function • nucleotide binding • GTP binding • protein binding • protein N-terminus binding • GTPase activity Cellular component • early endosome • acrosomal membrane • membrane • cytoplasmic vesicle • intracellular Biological process • small GTPase mediated signal transduction • positive regulation of collateral sprouting • signal transduction Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	8153	11858
Ensembl	ENSG00000108830	ENSMUSG00000001313
UniProt	P52198	Q9QYM5
RefSeq (mRNA)	NM_005440	NM_009708
RefSeq (protein)	NP_005431	NP_033838.1 NP_033838
Location (UCSC)	Chr 17: 43.03 – 43.03 Mb	Chr 11: 101.46 – 101.47 Mb
PubMed search

8153

11858

ENSG00000108830

ENSMUSG00000001313

P52198

Q9QYM5

NM_005440

NM_009708

NP_005431

NP_033838.1
NP_033838

Rnd2 is a small (~21 kDa) signaling G protein (to be specific, a GTPase), and is a member of the Rnd subgroup of the Rho family of GTPases. It is encoded by the gene RND2.

It contributes to regulating the organization of the actin cytoskeleton in response to extracellular growth factors (Nobes et al., 1998).[supplied by OMIM]

This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking.

The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1.

Rnd2 has been shown to interact with:

...
Wikipedia