Raphanin

Raphanin

Names
IUPAC name 4-Isothiocyanato-1-(methylsulfinyl)but-1-ene
Other names Sulforaphen; Sulforaphene; Sativin
Identifiers
CAS Number	592-95-0 Y
3D model (Jmol)	Interactive image
ChemSpider	16736047
PubChem	6433206
InChI InChI=1S/C6H9NOS2/c1-10(8)5-3-2-4-7-6-9/h3,5H,2,4H2,1H3 Key: QKGJFQMGPDVOQE-UHFFFAOYSA-N InChI=1/C6H9NOS2/c1-10(8)5-3-2-4-7-6-9/h3,5H,2,4H2,1H3 Key: QKGJFQMGPDVOQE-UHFFFAOYAU
SMILES S=C=N/CC\C=C\S(=O)C
Properties
Chemical formula	C6H9NOS2
Molar mass	175.26 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Raphanin is the main sulfur component found in radish seeds of Raphanus sativus and is also found in broccoli and red cabbage. It was first described by G. Ivanovics and S. Horvath in 1947. Raphanin inhibits activity of viruses, some fungi and various bacteria including Staphylococcus, , and Escherichia coli (see table). The effect is stronger against Gram-positive than Gram-negative bacteria and against DNA than RNA viruses; it is suppressed by serum and by sulfur compounds such as hydrogen sulfide, mercaptoacetic acid, cystine and glutathione. The antibacterial, antifungal and antiviral effects from consuming radishes were recognized in traditional Chinese medicine. Given that Raphanin can be chiefly responsible for keeping the production of thyroxine and calcitonin in normal balance, in Russia, radishes have long been used for treating both types of thyroid problems. However, in the abstract to his 1947 paper, Ivanovics noted that because raphanin is highly toxic, it did not "hold the promise of a useful therapeutic agent".