RRM2B

RRM2B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2VUX, 3HF1, 4DJN
Identifiers
Aliases	RRM2B, MTDPS8A, MTDPS8B, P53R2, ribonucleotide reductase regulatory TP53 inducible subunit M2B
External IDs	MGI: 2155865 HomoloGene: 56723 GeneCards: RRM2B
Gene location (Human) Chr. Chromosome 8 (human) Band 8q22.3 Start 102,204,502 bp End 102,239,118 bp
Gene location (Mouse) Chr. Chromosome 15 (mouse) Band 15|15 B3.1 Start 37,923,952 bp End 37,961,318 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • metal ion binding • protein binding • oxidoreductase activity • ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Cellular component • mitochondrion • extracellular exosome • nucleus • nucleoplasm • cytoplasm • cytosol • ribonucleoside-diphosphate reductase complex Biological process • deoxyribonucleoside triphosphate metabolic process • nucleobase-containing small molecule interconversion • renal system process • kidney development • response to oxidative stress • mitochondrial DNA replication • cellular response to DNA damage stimulus • deoxyribonucleotide biosynthetic process • DNA replication • negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator • response to amine • oxidation-reduction process • DNA repair Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	50484	382985
Ensembl	ENSG00000048392	ENSMUSG00000022292
UniProt	Q7LG56	Q6PEE3
RefSeq (mRNA)	NM_015713 NM_001172477 NM_001172478	NM_199476
RefSeq (protein)	NP_001165948 NP_001165949 NP_056528	NP_955770
Location (UCSC)	Chr 8: 102.2 – 102.24 Mb	Chr 8: 37.92 – 37.96 Mb
PubMed search

2VUX, 3HF1, 4DJN

50484

382985

ENSG00000048392

ENSMUSG00000022292

Q7LG56

Q6PEE3

NM_015713
NM_001172477
NM_001172478

NM_199476

NP_001165948
NP_001165949
NP_056528

NP_955770

Ribonucleoside-diphosphate reductase subunit M2 B is an enzyme that in humans is encoded by the RRM2B gene. The gene encoding the RRM2B protein is located on chromosome 8, at position 8q23.1. The gene and its products are also known by designations MTDPS8A, MTDPS8B, and p53R2.

...
Wikipedia