Chromosome 8 (human)
| Chromosome 8 (human) | |
|---|---|
Human chromosome 8 pair after G-banding.
One is from mother, one is from father. |
|
Chromosome 8 pair in human male karyogram.
|
|
| Features | |
| Length (bp) | 145,138,636 bp |
| No. of genes | 2,152 2,047 |
| Type | Autosome |
| Centromere position | Submetacentric |
| Identifiers | |
| RefSeq | NC_000008 |
| GenBank | CM000670 |
Chromosome 8 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 8 spans about 145 million base pairs (the building material of DNA) and represents between 4.5 and 5.0% of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies. In January 2017, two estimates differed by 5%, with one estimate giving 2,152 genes, and the other estimate giving 2,047 genes.
About 8% of its genes are involved in brain development and function, and about 16% are involved in cancer. A unique feature of 8p is a region of about 15 megabases that appears to have a high mutation rate. This region shows an significant divergence between human and chimpanzee, suggesting that its high mutation rates have contributed to the evolution of the human brain.
The following are some of the genes located on chromosome 8:
The following diseases and disorders are some of those related to genes on chromosome 8:
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Wikipedia