RNASEH2B

RNASEH2B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3P56, 3P87, 3PUF
Identifiers
Aliases	RNASEH2B, AGS2, DLEU8, ribonuclease H2 subunit B
External IDs	MGI: 1914403 HomoloGene: 41572 GeneCards: RNASEH2B
Gene location (Human) Chr. Chromosome 13 (human) Band 13q14.3 Start 50,909,678 bp End 50,973,745 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 D1 Start 62,292,589 bp End 62,372,992 bp
Gene ontology Molecular function • RNA-DNA hybrid ribonuclease activity Cellular component • nucleus • ribonuclease H2 complex Biological process • regulation of G2/M transition of mitotic cell cycle • RNA catabolic process • in utero embryonic development • RNA phosphodiester bond hydrolysis, endonucleolytic • ribonucleotide metabolic process • regulation of DNA damage checkpoint • negative regulation of gene expression • positive regulation of fibroblast proliferation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	79621	67153
Ensembl	ENSG00000136104	ENSMUSG00000021932
UniProt	Q5TBB1 Q8N451	Q80ZV0
RefSeq (mRNA)	NM_001142279 NM_024570	NM_026001
RefSeq (protein)	NP_001135751 NP_078846 NP_078846.2	NP_080277
Location (UCSC)	Chr 13: 50.91 – 50.97 Mb	Chr 13: 62.29 – 62.37 Mb
PubMed search

3P56, 3P87, 3PUF

79621

67153

ENSG00000136104

ENSMUSG00000021932

Q5TBB1
Q8N451

Q80ZV0

NM_001142279
NM_024570

NM_026001

NP_001135751
NP_078846
NP_078846.2

NP_080277

Ribonuclease H2, subunit B is a protein that in humans is encoded by the RNASEH2B gene.RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C), and degrades the RNA of RNA:DNA hybrids. The non-catalytic B subunit of RNase H2 is thought to play a role in DNA replication.

...
Wikipedia