RHCG

RHCG
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3HD6
Identifiers
Aliases	RHCG, C15orf6, PDRC2, RHGK, SLC42A3, Rh family C glycoprotein
External IDs	MGI: 1888517 HomoloGene: 32310 GeneCards: RHCG
Gene ontology Molecular function • ankyrin binding • ammonium transmembrane transporter activity Cellular component • integral component of membrane • membrane • plasma membrane • integral component of plasma membrane • basolateral plasma membrane • apical plasma membrane • extracellular exosome • cytoplasmic vesicle Biological process • ammonium transmembrane transport • epithelial cell differentiation • amine transport • ammonium transport • organic cation transport • transepithelial ammonium transport • transport • cellular ion homeostasis • regulation of pH • homeostatic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	51458	56315
Ensembl	ENSG00000140519	ENSMUSG00000030549
UniProt	Q9UBD6	Q9QXP0
RefSeq (mRNA)	NM_016321 NM_001321041	NM_019799
RefSeq (protein)	NP_001307970 NP_057405	NP_062773.2 NP_062773
Location (UCSC)	Chr 15: 89.47 – 89.5 Mb	Chr 7: 79.59 – 79.62 Mb
PubMed search

3HD6

51458

56315

ENSG00000140519

ENSMUSG00000030549

Q9UBD6

Q9QXP0

NM_016321
NM_001321041

NM_019799

NP_001307970
NP_057405

NP_062773.2
NP_062773

Rh family, C glycoprotein, also known as RHCG, is a protein that in humans is encoded by the RHCG gene.

RHCG plays a critical role in ammonium handling and pH homeostasis in the kidney. The structure of the RHCG protein indicates that it has a hydrophobic ammonia-conducting channel and shows that it shares a common fold with the ammonia transporters, thus making it an ammonia transporter.

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Wikipedia