| Route 216 | ||||
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| Maintained by Transports Québec | ||||
| Length: | 315.5 km (196.0 mi) | |||
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Route 216 is a two-lane east/west highway in Quebec, Canada, which starts in Sainte-Catherine-de-Hatley in the Estrie region at the junction of Route 108 and ends in Sainte-Perpétue in Chaudière-Appalaches at the junction of Route 204.
Route 216 follows mostly a northeast/southwest course, and it is not a busy highway as it mostly links small villages between themselves in the backroads of the Appalachians. The only two major towns along the way are Sherbrooke and Sainte-Marie. Between Ham-Nord and Kinnear's Mills, very long stretches of the road are gravel.