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Q-fever

Q fever
Immunohistochemical detection of C. burnetii in resected cardiac valve of a 60-year-old man with Q fever endocarditis, Cayenne, French Guiana: Monoclonal antibodies against C. burnetii and hematoxylin were used for staining; original magnification is ×50.
Classification and external resources
Specialty infectious disease
ICD-10 A78
ICD-9-CM 083.0
DiseasesDB 11093
MedlinePlus 001337
eMedicine med/1982 ped/1973
Patient UK Q fever
MeSH D011778
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Q fever is a disease caused by infection with Coxiella burnetii, a bacterium that affects humans and other animals. This organism is uncommon, but may be found in cattle, sheep, goats, and other domestic mammals, including cats and dogs. The infection results from inhalation of a spore-like small-cell variant, and from contact with the milk, urine, feces, vaginal mucus, or semen of infected animals. Rarely, the disease is tick-borne. The incubation period is 9–40 days. Humans are vulnerable to Q fever, and infection can result from even a few organisms.Persons in direct contact with animals during birthing, such as veterinarians may be at a higher risk for infection. The bacterium is an obligate intracellular pathogenic parasite. C. burnetii can survive for a long time in the enviornment and can be carried long distances through the wind.

Incubation period is usually two to three weeks. The most common manifestation is flu-like symptoms with abrupt onset of fever, malaise, profuse perspiration, severe headache, muscle pain, joint pain, loss of appetite, upper respiratory problems, dry cough, pleuritic pain, chills, confusion, and gastrointestinal symptoms, such as nausea, vomiting, and diarrhea. About half of infected individuals exhibit no symptoms.


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