Pyruvate dehydrogenase phosphatase

PDP1

Identifiers

PDP1, PDH, PDP, PDPC, PPM2C, PPM2A, pyruvate dehyrogenase phosphatase catalytic subunit 1

External IDs

OMIM: 605993 MGI: 2685870 HomoloGene: 31928 GeneCards: PDP1

Gene location (Human)

Chr.	Chromosome 8 (human)

Band	8q22.1	Start	93,857,807 bp
Band	8q22.1	End	93,926,066 bp

Gene location (Mouse)

Chr.	Chromosome 4 (mouse)

Band	4\|4 A1	Start	11,958,184 bp
Band	4\|4 A1	End	11,966,452 bp

Gene ontology
Molecular function	• protein serine/threonine phosphatase activity • protein binding • catalytic activity • phosphoprotein phosphatase activity • hydrolase activity • cation binding • metal ion binding • [pyruvate dehydrogenase (lipoamide) phosphatase activity]
Cellular component	• mitochondrial matrix • mitochondrion
Biological process	• protein dephosphorylation • regulation of acetyl-CoA biosynthetic process from pyruvate • peptidyl-threonine dephosphorylation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


54704


381511


ENSG00000164951


ENSMUSG00000049225


Q9P0J1


Q3UV70

RefSeq (mRNA)


NM_001161778 NM_001161779 NM_001161780 NM_001161781 NM_018444


NM_001033453 NM_001098230 NM_001098231 NM_001290387 NM_001290391

RefSeq (protein)


NP_001155251 NP_001155252 NP_001155253 NP_060914


NP_001028625 NP_001091700 NP_001091701 NP_001277316 NP_001277320

Location (UCSC)

Chr 8: 93.86 – 93.93 Mb

Chr 8: 11.96 – 11.97 Mb

PubMed search

ENSG00000164951

ENSMUSG00000049225

NM_001161778
NM_001161779
NM_001161780
NM_001161781
NM_018444

NM_001033453
NM_001098230
NM_001098231
NM_001290387
NM_001290391

NP_001155251
NP_001155252
NP_001155253
NP_060914

NP_001028625
NP_001091700
NP_001091701
NP_001277316
NP_001277320

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Wikipedia

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