Providone-iodine
Povidone-iodine applied to an abrasion using a cotton swab.
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| Trade names | Wokadine, Pyodine, Betadine, others |
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| Synonyms | polyvidone iodine, iodopovidone |
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| ECHA InfoCard | 100.110.412 |
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| Formula | (C6H9NO)n·xI |
| Molar mass | variable |
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Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery. It may be used both to disinfect the skin of the patient and the hands of the healthcare providers. It may also be used for minor wounds. It may be applied to the skin as a liquid or a powder.
Side effects include skin irritation. If used on large wounds kidney problems, high blood sodium, and metabolic acidosis may occur. It is not recommended in people who are less than 32 weeks pregnant or are taking lithium. Frequent use is not recommended in people with thyroid problems. Povidone-iodine is a chemical complex of povidone, hydrogen iodide, and elemental iodine. It contains from 9% to 12% available iodine. It works by releasing iodine which results in the death of a range of microorganisms.
Povidone-iodine came into commercial use in 1955. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Povidone-iodine is available over the counter. The wholesale cost in the developing world is about 3.30 to 11.40 USD per liter of 10% solution. This amount in the United Kingdom cost the NHS about 10.86 pounds. It is sold under a number of brand names including Betadine.
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