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Povidone

Polyvinylpyrrolidone
150pxc
Sample of polyvinyl pyrrolidone.jpg
Names
IUPAC name
1-ethenylpyrrolidin-2-one
Other names
PVP, Povidone, Copovidone

PVPP, Crospovidone, Polyvidone
PNVP
Poly[1-(2-oxo-1-pyrrolidinyl)ethylen]
1-Ethenyl-2-pyrrolidon homopolymer

1-Vinyl-2-pyrrolidinon-Polymere
Identifiers
9003-39-8 YesY
3D model (Jmol) Interactive image
Abbreviations PVP, PVPP, NVP, PNVP
ChEMBL ChEMBL1909074 N
ECHA InfoCard 100.111.937
E number E1201 (additional chemicals)
Properties
(C6H9NO)n
Molar mass 2.500 – 2.500.000 g·mol−1
Appearance white to light yellow, hygroscopic, amorphous powder
Density 1.2 g/cm3
Melting point 150 to 180 °C (302 to 356 °F; 423 to 453 K) (glass temperature)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YesYN ?)
Infobox references

PVPP, Crospovidone, Polyvidone
PNVP
Poly[1-(2-oxo-1-pyrrolidinyl)ethylen]
1-Ethenyl-2-pyrrolidon homopolymer

Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone:

PVP was used as a plasma volume expander for trauma victims after the 1950s.

It is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally. However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption. The long-term effects of crospovidone or povidone within the lung are unknown. PVP added to iodine forms a complex called povidone-iodine that possesses disinfectant properties. This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine among a plethora of others.

It is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.

Povidone is used as a lubricant in some eye drops, e.g. Bausch & Lomb's Soothe.

PVP is also used in many technical applications:

PVP binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers.


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Wikipedia

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