Hypernatremia | |
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Sodium | |
Classification and external resources | |
Specialty | Internal medicine |
ICD-10 | E87.0 |
ICD-9-CM | 276.0 |
DiseasesDB | 6266 |
eMedicine | emerg/263 |
Patient UK | Hypernatremia |
Hypernatremia, also spelled hypernatraemia, is a high sodium ion level in the blood. Early symptoms may include a strong feeling of thirst, weakness, nausea, and loss of appetite. Severe symptoms include confusion, muscle twitching, and bleeding in or around the brain. Normal serum sodium levels are 135 - 145 mmol/L (135 - 145 mEq/L). Hypernatremia is generally defined as a serum sodium level of more than 145 mmol/L. Severe symptoms typically only occur when levels are above 160 mmol/L.
Hypernatremia is typically classified by a person's fluid status into low volume, normal volume, and high volume. Low volume hypernatremia can occur from sweating, vomiting, diarrhea, diuretic medication, or kidney disease. Normal volume hypernatremia can be due to fever, inappropriately decreased thirst, prolonged increased breath rate, diabetes insipidus, and from lithium among other causes. High volume hypernatremia can be due to hyperaldosteronism, be health care caused such as when too much intravenous 3% normal saline or sodium bicarbonate is given, or rarely be from eating too much salt.Low blood protein levels can result in a falsely high sodium measurement. The cause can usually be determined by the history of events. Testing the urine can help if the cause is unclear.