Frederick, Prince of Orange-Nassau (English: William George Frederick, Dutch: Willem George Frederik; 15 February 1774 – 6 January 1799) was the youngest son of William V, Prince of Orange and Stadtholder of the Dutch Republic and Princess Wilhelmina of Prussia, sister of King Frederick William II. Commonly called Fritz inside the family, he chose a military career with the Holy Roman Empire, he died of a fever while serving in Padua, Italy.

Prince Frederick, or "Fritz", as members of his family called him, was born in The Hague during the Dutch Republic period. His parents, William V and Princess Wilhelmina, already had two children: Frederica Louise Wilhelmina (1770–1819) and Willem Frederik (1772–1843); Louise would later marry the Hereditary Prince of Brunswick-Wolfenbüttel and Willem would become the first Dutch King. Frederick was related to the British royal family through both his father, who was the grandson of George II of Great Britain, and through his mother, who was the grandniece of George II.

Even as a young boy, he was bright and showed much promise in the military field; General Prince Frederick Stamford, mathematician Leonhard Euler and historian Herman Tollius were among his tutors. After military training in Brunswick, where his cousin once removed was reigning duke, Prince Frederick began active military service in 1792 when the States-General granted him the rank of lieutenant-general of the cavalry and grand master of artillery. In 1793, he was called to war when the Republic had to be defended against the French. He was an inspiring leader and was usually in the forefront. Prince Frederick took upon himself the defense of the northwestern part of Brabant. Later, he served under his older brother at Veurne (Furnes) and Menin (Menen). While fighting in the latter battle at Flemish Wervik, on 12/13 September 1793, Frederick suffered an injury when he was shot in the shoulder; this was an injury he never fully recovered from. In 1794, he was appointed general of the cavalry.

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