Plasmodium ovale

Plasmodium ovale
Plasmodium ovale trophozoite, Giemsa stain.
Scientific classification
Domain:	Eukaryota
(unranked):	SAR
(unranked):	Alveolata
Phylum:	Apicomplexa
Class:	Aconoidasida
Order:	Haemosporida
Family:	Plasmodiidae
Genus:	Plasmodium
Species:	P. ovale
Binomial name
Plasmodium ovale Stephens 1922

Plasmodium ovale is a species of parasitic protozoa that causes tertian malaria in humans. It is one of several species of Plasmodium parasites that infect humans including Plasmodium falciparum and Plasmodium vivax which are responsible for most malarial infection. It is rare compared to these two parasites, and substantially less dangerous than P. falciparum.

P. ovale has recently been shown by genetic methods to consist of two subspecies, P. ovale curtisi and P. ovale wallikeri.

This species was first described in 1914 by Stephens in a blood sample taken in the autumn of 1913 from a patient in the sanitarium of Pachmari in central India and sent by Major W. H. Kenrick to Stephens (who was working in Liverpool).

P. ovale is primarily concentrated in sub-Saharan Africa and islands in the western Pacific. However P. ovale has also been reported in the Philippines, eastern Indonesia, and Papua New Guinea, as well as Bangladesh ,Cambodia,India,Thailand and Vietnam

In several studies, the reported prevalence of P. ovale was low relative to other malaria parasites, with fewer than 5% of malaria cases being associated with P. ovale infection. Higher prevalences of P. ovale are possible under certain conditions, as at least one study in Cameroon found the prevalence of P. ovale infection to be greater than 10%.

It has been estimated that there are about 15 million cases of infection each year with this parasite.

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