The Jezreel Valley (Hebrew: עמק יזרעאל, translit. Emek Yizra'el), (Arabic: مرج إبن عامر "Marj Ibn Āmir") is a large fertile plain and inland valley south of the Lower Galilee region in Israel. The Samarian highlands and Mount Gilboa border the valley from the south and to the north lie the Israeli cities Afula and Tiberias. To the west is the Mount Carmel range, and to the east is the Jordan Valley.
The Jezreel Valley takes its name from the ancient city of Jezreel (known in Arabic as Zir'ēn; Arabic: زرعين) which was located on a low hill overlooking the southern edge of the valley. The word Jezreel comes from the Hebrew, and means "God sows" or "El sows". The phrase "valley of Jezreel" was sometimes used to refer to the central part of the valley, around the city of Jezreel, while the southwestern portion was known as the "valley of Megiddo", after the ancient city of Megiddo, which was located there. The area has been known as the Plain of Esdraelon (Esdraelon is the Koine Greek rendering of Jezreel).
The valley perhaps once acted as the channel by which the Dead Sea, located southeast of the valley, connected to the Mediterranean Sea. About two million years ago, as the land between the Mediterranean Sea and the Jordan Rift Valley rose, this connection was lost, and periodic floods from the Mediterranean Sea ceased. This resulted in the Dead Sea no longer having a connection to the ocean, and over time, due to greater evaporation than precipitation plus surface water inflow, it has become heavily saline.