PRKAR1B

PRKAR1B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4DIN, 4F9K
Identifiers
Aliases	PRKAR1B, PRKAR1, protein kinase cAMP-dependent type I regulatory subunit beta
External IDs	MGI: 97759 HomoloGene: 37665 GeneCards: PRKAR1B
Gene ontology Molecular function • nucleotide binding • protein kinase A catalytic subunit binding • cAMP binding • cAMP-dependent protein kinase regulator activity • cAMP-dependent protein kinase inhibitor activity • protein binding Cellular component • cytosol • membrane • plasma membrane • ciliary base • cAMP-dependent protein kinase complex Biological process • regulation of protein phosphorylation • activation of protein kinase A activity • cellular response to glucagon stimulus • blood coagulation • negative regulation of cAMP-dependent protein kinase activity • protein phosphorylation • renal water homeostasis • learning or memory Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	5575	19085
Ensembl	ENSG00000188191	ENSMUSG00000025855
UniProt	P31321	P12849
RefSeq (mRNA)	NM_001164758 NM_001164759 NM_001164760 NM_001164761 NM_001164762 NM_002735	NM_001253890 NM_008923
RefSeq (protein)	NP_001158230 NP_001158231 NP_001158232 NP_001158233 NP_001158234 NP_002726	NP_001240819 NP_032949
Location (UCSC)	Chr 7: 0.55 – 0.73 Mb	Chr 5: 139.02 – 139.15 Mb
PubMed search

4DIN, 4F9K

5575

19085

ENSG00000188191

ENSMUSG00000025855

P31321

P12849

NM_002735

NM_001253890
NM_008923

NP_002726

NP_001240819
NP_032949

cAMP-dependent protein kinase type I-beta regulatory subunit is an enzyme that in humans is encoded by the PRKAR1B gene.

Mutations in PRKAR1B cause neurodegenerative disorder .

PRKAR1B has been shown to interact with AKAP1 and PRKAR1A.

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Wikipedia