PRKAR1A

PRKAR1A

Protein PRKAR1A PDB 1ne4.png

Identifiers

PRKAR1A, ACRDYS1, ADOHR, CAR, CNC, CNC1, PKR1, PPNAD1, PRKAR1, TSE1, protein kinase cAMP-dependent type I regulatory subunit alpha

External IDs

MGI: 104878 HomoloGene: 37664 GeneCards: PRKAR1A

Gene ontology
Molecular function	• nucleotide binding • protein kinase A catalytic subunit binding • cAMP binding • protein binding • cAMP-dependent protein kinase regulator activity • cAMP-dependent protein kinase inhibitor activity • ubiquitin protein ligase binding • kinase activity
Cellular component	• cytoplasm • cytosol • membrane • plasma membrane raft • neuromuscular junction • plasma membrane • protein complex • ciliary base • nucleotide-activated protein kinase complex • immunological synapse • cAMP-dependent protein kinase complex
Biological process	• regulation of protein phosphorylation • activation of protein kinase A activity • intracellular signal transduction • negative regulation of protein kinase activity • regulation of transcription from RNA polymerase II promoter • cellular response to glucagon stimulus • mesoderm formation • blood coagulation • female meiotic division • negative regulation of meiotic nuclear division • cardiac muscle cell proliferation • negative regulation of cAMP-dependent protein kinase activity • negative regulation of activated T cell proliferation • heart development • renal water homeostasis • regulation of protein kinase activity • sarcomere organization • phosphorylation
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE PRKAR1A 200605 s at fs.png

PBB GE PRKAR1A 200603 at fs.png

PBB GE PRKAR1A 200604 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


5573


19084


ENSG00000108946


ENSMUSG00000020612


P10644


Q9DBC7

RefSeq (mRNA)

NM_001276289 NM_001276290 NM_001278433 NM_002734 NM_212471
NM_212472


NM_021880 NM_001313973 NM_001313974 NM_001313975 NM_001313976

RefSeq (protein)

NP_001263218 NP_001263219 NP_001265362 NP_002725 NP_997636
NP_997637 NP_001263218.1 NP_001265362.1 NP_002725.1 NP_997636.1 NP_997637.1

NP_001300902.1 NP_001300903.1 NP_001300904.1 NP_001300905.1 NP_068680.1
NP_001300902 NP_001300903 NP_001300904 NP_001300905 NP_068680

Location (UCSC)

Chr 17: 68.51 – 68.55 Mb

Chr 11: 109.65 – 109.67 Mb

PubMed search

ENSG00000108946

ENSMUSG00000020612

NM_021880
NM_001313973
NM_001313974
NM_001313975
NM_001313976

NP_997637
NP_001263218.1
NP_001265362.1
NP_002725.1
NP_997636.1
NP_997637.1

NP_001300902
NP_001300903
NP_001300904
NP_001300905
NP_068680

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Wikipedia

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