POLA2

POLA2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2KEB, 4E2I, 4Y97, 5EXR
Identifiers
Aliases	POLA2, DNA polymerase alpha 2, accessory subunit
External IDs	MGI: 99690 HomoloGene: 48121 GeneCards: POLA2
Gene ontology Molecular function • DNA binding • DNA-directed DNA polymerase activity • protein heterodimerization activity Cellular component • alpha DNA polymerase:primase complex • nucleus • nucleoplasm • cytosol Biological process • G1/S transition of mitotic cell cycle • DNA replication • protein import into nucleus, translocation • DNA biosynthetic process • DNA replication initiation • telomere maintenance via semi-conservative replication Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23649	18969
Ensembl	ENSG00000014138	ENSMUSG00000024833
UniProt	Q14181	P33611
RefSeq (mRNA)	NM_002689	NM_001164057 NM_008893
RefSeq (protein)	NP_002680	NP_001157529 NP_032919
Location (UCSC)	Chr 11: 65.26 – 65.31 Mb	Chr 19: 5.94 – 5.96 Mb
PubMed search

2KEB, 4E2I, 4Y97, 5EXR

23649

18969

ENSG00000014138

ENSMUSG00000024833

Q14181

P33611

NM_002689

NM_001164057
NM_008893

NP_002680

NP_001157529
NP_032919

DNA polymerase alpha subunit 2 is an enzyme that in humans is encoded by the POLA2 gene.

POLA2 has been shown to interact with PARP1.

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Wikipedia