PLXNB2

PLXNB2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4E71
Identifiers
Aliases	PLXNB2, MM1, Nbla00445, PLEXB2, dJ402G11.3, plexin B2
External IDs	MGI: 2154239 HomoloGene: 66630 GeneCards: PLXNB2
Gene ontology Molecular function • protein binding • semaphorin receptor activity Cellular component • integral component of membrane • membrane • plasma membrane • cell surface • extracellular exosome • integral component of plasma membrane Biological process • regulation of protein phosphorylation • negative regulation of cell adhesion • regulation of GTPase activity • positive regulation of axonogenesis • multicellular organism development • neural tube closure • brain development • regulation of cell shape • neuroblast proliferation • regulation of neuron migration • semaphorin-plexin signaling pathway • signal transduction • positive regulation of neuron projection development • homophilic cell adhesion via plasma membrane adhesion molecules Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23654	140570
Ensembl	ENSG00000196576	ENSMUSG00000036606
UniProt	O15031	B2RXS4
RefSeq (mRNA)	NM_012401	NM_001159521 NM_001284506 NM_138749
RefSeq (protein)	NP_036533	NP_001152993.1 NP_001271435.1 NP_620088.2 NP_001152993 NP_001271435 NP_620088
Location (UCSC)	Chr 22: 50.27 – 50.31 Mb	Chr 15: 89.16 – 89.17 Mb
PubMed search

4E71

23654

140570

ENSG00000196576

ENSMUSG00000036606

O15031

B2RXS4

NM_012401

NM_001159521
NM_001284506
NM_138749

NP_036533

NP_620088

Plexin-B2 is a protein that in humans is encoded by the PLXNB2 gene.

Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002)).[supplied by OMIM]

PLXNB2 has been shown to interact with ARHGEF11.

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Wikipedia